Welcome Message


Our lab is interested in the systems biology and evolution of epigenetic switches (bistability) and clocks (oscillators) in gene regulatory networks, two functions that are essential for proper patterning, cell proliferation, and cellular differentiation in biological systems.

Bass Connections & Duke iGEM team

indexThe Duke iGEM team works to promote synthetic biology both in and out of the lab. The team also interfaces with faculty engaged in public policy and ethics to explore synthetic biology’s legal, ethical, and economic impact. The results of the project are submitted to the iGEM competition to be held in Boston in Fall 2015.  Interested faculty, graduate students, and undergraduates are encourage to apply through our Bass Connections program.

Matthew Faw and Matthew Farnitano (two undergraduate members of our Duke iGEM team) are teaching a Duke House Course on “Creating Life:  The Emergence of Synthetic Biology”.

Buchler lab at ASCB 2014

indexTony Burnetti presented his work “Entry into oxidative phase is tightly coupled to the cell cycle in diverse strains and growth conditions“ at the 2014 ASCB annual meeting in Philadelphia. Nick Buchler also presented “Measuring fast gene dynamics in single cells with time-lapse luminescence microscopy“, which was highlighted in the December 2014 ASCB newsletter; read more here.