Evolution of G1-S cell cycle control

Read our evolutionary perspective on G1-S regulation in yeasts and mammals, where network topology and its associated dynamic properties (rather than regulatory proteins) appear to be the most important elements conserved through evolution.

Cross FR, Buchler NE, Skotheim JM. Evolution of networks and sequences in eukaryotic cell cycle control. Phil. Trans. R. Soc. B 2011; 366: 3532-3544.